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High homocysteine can be an indirect marker / indicator of B12 deficiency

Common B12 deficiency symptoms include fatigue, anxiety, depression, poor memory, confusion, brain fog, tingling or numbness in the extremities, zings or zapping feelings in the extremities, anemia, shortness of breath, muscle weakness, irritability, tender calves, pale complexion and more

Some Sources of Vitamin B12 Vitamin B12 occurs naturally in many everyday foods, such as: Meat Fish Dairy Eggs Some fortified cereals Why Are Three B Vitamins Better Than One

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Diet and exercise A calorie deficit or new training plan may explain the result even when a compound was also used