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It is postulated that ADHD may result from deficits in the dopaminergic system in cortical brain structures such as the prefrontal cortex, subcortical areas such as striatum [54, 55]

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Sample Preparation Desalting and buffer exchange Enzymatic digestion for peptide mapping Minimizing peptide adsorption and degradation Proper sample preparation helps prevent contamination and reduces signal suppression during LC-MS analysis