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Following digestion of pC210 with Nde I and Sph I to remove the SSA1 coding sequence, similarly digested gliT PCR product was ligated into pC210 to create pC-GliT

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The G6PD Mediterranean variant is a Class II variant, thus more severe, and typically affects Italian, Grecian, Spanish, Arabic, and certain Kurdish populations

And previous studies in our laboratory have shown that conversion of Cys residues into Sec residues in GPx1 and GPx4 could result in dramatic loss of the catalytic activity 15,16

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By repairing the intestinal barrier, not just reducing inflammation, it addresses the root causes of chronic digestive issues