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Collagen density increase: Punch biopsy samples analyzed via Massons trichrome staining showed 18-22% increase in dermal collagen density after 8 weeks of topical application
To assess its global efficacy, scientists looked at four randomized controlled trials, all including patients with neuropathy secondary to diabetes and to anti-retroviral therapy for HIV
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while 6 subjects (15.4%) in the EGCG group and 2 subjects (5.3%) in the placebo group took the lipid modifying medications
Similar results were observed across the individual components of MACE, with the exception of CV death in subjects with a prior MI or stroke or with established CVD (p = 0.22 for interaction between subjects with prior MI or stroke vs no prior MI or stroke
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