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In the SURMOUNT-4 trial, participants who stopped tirzepatide after 36 weeks regained an average of around 14% of their body weight within the following year, although at 88 weeks the group that stopped had still maintained around 10% of their original weight loss overall

Exposure to albumin changed intracellular metabolite pools as early as 3 h after exposure, which became more pronounced after 24 h (Fig

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