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As a supplement that can potentially boost GLP-1 levels by enhancing insulin sensitivity , there is limited evidence for this claim , and more research is needed

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Clinically, oral L-serine has shown good tolerability in early studies targeting neurological conditions such as amyotrophic lateral sclerosis and sensory neuropathies, although efficacy remains limited and further investigation is warranted 146,147

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References: [1] FDA, Vyleesi, June 2919 [2] Mayo Clinic, Vyleesi, January 2026 [3] National Library of Medicine, Bremelanotide, Dhillon, S., Keam, S.J., September, 2019