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Conclusion: There is much scope for intense research to understand glutathione in relation to the augmentation of skin lightening

A similar outcome appears in the CO 2 laser injury on the dorsal skin mice ( FIGURE 1 To find out a specific mechanism, a comparison with the becaplermin (recombinant human plateletderived growth factor homodimer of B chains, PDGF-BB) was the focus of the two additional studies using excisional wounds in diabetic rats and mice (Figure 2) (Seveljevic-Jaran et al., 2006

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Human dermal fibroblast studies show up to 70% increase in collagen production at optimal 1 nanomolar concentration, with collagen IV showing 25.4-fold increase when combined with hyaluronic acid

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