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Similar findings were replicated in the study population with T2D when comparing semaglutide with non-GLP-1RA anti-diabetes medications for incident CUD (HR: 0.40, 95% CI: 0.290.56) and recurrent CUD (HR: 0.66, 95% CI: 0.421.03)
NAM levels are regulated by nicotinamide N-methyltransferase (NNMT), which converts NAM to methylnicotinamide (meNAM) 57 (Fig
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