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Food-bound B12 must first be released by gastric acid and pepsin
It has been observed that short acting GLP-1 receptor agonists exert their primary hypoglycemic effect by lowering postprandial glucose due to their inhibitory effect on gastric emptying
For B12 injections, needles with lengths between 1 to 1.5 inches are often recommended
The proposed mechanism of action of these peptides is that they enter the hind-brain from the peripheral bloodstream, and interact directly with GLP-1 receptors in the brain - possibly the parabrachial nucleus (Kanoski et al., 2016)
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