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At the 12mg dose, Phase 2 participants averaged about 24 percent body weight loss over 48 weeks, and the larger Phase 3 TRIUMPH-4 trial reported close to 29 percent at 68 weeks, an average of roughly 71 pounds

They often occur during the first weeks of treatment and after dose increases, then resolve or become infrequent

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It works by regulating appetite, slowing gastric emptying, and improving blood sugar control, not by thinning the blood

[1] [2] The tablet should be swallowed whole and not split, crushed or chewed

However, the underutilization of GLP-1 RAs represents a significant opportunity to improve post-transplant outcomes in this high-risk population