PT-141 is a synthetic cyclic lactam heptapeptide analogue of alpha-melanocyte-stimulating hormone, sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (CHNO, 1025.2 g/mol, CAS 189691-06-3), and its international non-proprietary name is bremelanotide
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Simultaneously, the World Health Organization (WHO) estimates that over 1 billion people globally are living with obesity
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Stability: GHK-Cu is enzymatically degraded by serum proteases relatively quickly, which is why topical formulations often include penetration enhancers (like DMSO or liposomes) to improve dermal delivery before breakdown occurs