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Physiology-Endocrinology Metabolism

Monitoring and Follow-Up Regular follow-up is essential with either medication

As compared to loop diuretics, SGLT2-i may distinctly regulate the interstitial versus intravascular compartment selectively reducing interstitial oedema, which has been observed in HF and DKD, with minimal change in blood volume

The timing consideration isn't about separation windows

Injection sites: Subcutaneous injection into fatty tissue Abdomen (2 inches from navel) Thighs Upper arm Rotate injection locations to minimize irritation