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Despite its impressive TRIUMPH-1 results, this groundbreaking medication must clear further regulatory hurdles before reaching patients
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daily or weekly) to correct deficiency, followed by maintenance (commonly 1 mg IM monthly or as prescribed)
PubMed DOI
53 Therapeutic targeting of cardiac proteostasis The recognition that proteostasis failure contributes directly to cardiovascular disease has accelerated the development of therapeutic strategies aimed at restoring protein quality control rather than targeting isolated downstream manifestations
Nature Aging , 1, 760777
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