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Stopping semaglutide usually leads to a return of appetite, which can cause weight regain and higher blood sugar in people with diabetes
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A promising pharmacological strategy to circumvent this has been made in the treatment of obesity and the metabolic syndrome, via the integration of multiple mechanisms within a single molecule [18, 69]
The goal is to harness the powerful potential of these compounds safely and effectively
But in a surprising twist, top-line results show higher dropout rates than in earlier trials, with at least some participants worried about just how slim they were becoming
Frontiers in Pharmacology, 12, 627533
