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10.1016/j.bbrc.2022.10.065 127 YeZ.LiuW.ZhuoQ.HuQ.LiuM.SunQ.et al (2020)

However, obesity-related complications (diabetes, heart disease, sleep apnea) remain the major risk factors affecting life expectancy

This is known as the Lands cycle

The lower rate of non-CV deaths was because of lower infectious deaths, in particular COVID-19related deaths, suggesting that semaglutide has a favorable outcome in terms of mortality across a broad population of patients with CV disease and obesity (88)

Or drop coverage and devastate the employees who depended on it

Lifestyle changes have led to a surge in the incidence of obesity and type 2 diabetes, correlating to the increasing global prevalence of MASH (Fig.1)