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and favorable renal hemodynamic effects that lessen cardiorenal stress as demonstrated in Fig

These alterations contribute to mitochondrial dysfunction, insulin resistance (IR), and the pathogenesis of sarcopenia [39, 81]

You, L., Sar, M., Bartolucci, E., Ploch, S

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This section delineates SFNs multifaceted mechanisms across epigenetic regulation, programmed cell death pathways (particularly ferroptosis), and tumor immune microenvironment remodeling, establishing its role as a truly multi-targeted therapeutic agent