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We actually prefer SQ because its painless and has an established track record of effective B12 delivery, whereas IM can be painful and tends to put people off self-injecting
Our team has observed that for studies focusing on long-term, sustained NNMT inhibition where slight variations in peak plasma concentration aren't catastrophic, the oral route might be sufficient
A deficiency of vitamin B12 can also cause shortness of breath or heart palpitations, as well as gastrointestinal symptoms including constipation, diarrhea, appetite loss, or gas
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This is one reason the loading schedule is medically supervised rather than something to rush
Its critical to note, though, that it was the combined high intake of vitamins B6 and B12
The abdominal region is the preferred injection site, though thighs and upper arms are acceptable alternatives
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