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Others include glucose-dependent insulinotropic polypeptide (GIP), ghrelin, peptide YY (PYY) and pancreatic polypeptide (PP) (1)
When they fail to do so, they can be held accountable
Similarly, ONCOS-102, an engineered adenovirus expressing GM-CSF, has been tested with pembrolizumab in advanced melanoma (NCT03003676), aiming to activate dendritic cells and potentiate T-cellmediated responses
Risk factors include rapid up-titration
The plunger design incorporates a dome and optimised dimensions allowing it to fit perfectly into the syringe barrel design
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