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Previous studies in mice have reported that matched, unbiased agonists are less effective at controlling glucose and body weight than GLP-1RAs with bias similar to that of tirzepatide [35, 36]

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(PubMed) Leppala JM, Virtamo J, Fogelholm R, et al

[] Research has shown that mKl binds to FGF receptor 1 (FGFR1) to form a Kl/FGFR1 binary complex, which binds to FGF23 to form the Kl/FGFR1/FGF23 ternary complex

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