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The agency determined that there is no longer a justification for large-scale compounding because FDA-approved versions are available and recent shortages are largely resolved
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Research participants on semaglutide at maintenance doses showed an average of 15 to 17% body weight reduction over 68 weeks in the landmark clinical trials
Human thyroid C-cells have substantially lower GLP-1 receptor density compared to rodents, which may reduce susceptibility to GLP-1-mediated proliferative effects
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