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The therapeutic lag of these medications (typically 2 to 4 weeks) correlates with the time required for BDNF-driven neuroplastic changes to take effect
Khavinson VK, Bondarev IE, Butyugov AA
The condition involves inflammation and micro-tearing of the plantar fascia, a thick band of connective tissue that runs along the bottom of your foot from the heel bone to the toes
Outcomes appear highly context-dependent, reinforcing the need for controlled experimental design and continued mechanistic research
I've brought this up before on this forum and got all the same kind of advice you got, and I do everything properly, and I've been doing it once or twice a week for years, so for me it's just become a fact of life that it's going to hurt
The Journal of Biochemistry, 175 (5), 473-480
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