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These microbial alterations of metabolic liver disease were associated with increased concentrations of molecules like 2-butanone and 4-methyl-2-pentanone that are responsible of toxic effect in hepatocytes [48]

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Preclinical research suggests involvement in biological processes (angiogenesis, collagen formation, cellular signaling), which are linked to tissue healing and inflammation control

This results in an increasing number of clinical trials

Serine is a natural ligand and allosteric activator of pyruvate kinase M2