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Slides were rinsed three times with Tris buffer and counterstained with DAPI (Sigma-Aldrich, 1:2500) for 1 minute in darkness
Regulation of redox-sensitive signaling pathways in rat primary astrocytes following acrolein exposure
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Detoxification Support Glutathione is a key player in the bodys detoxification pathways: Glutathione attaches to environmental pollutants and heavy metals to help remove these toxins from the body
7 In fact, xCT is considered to be the main transporter of cystine in cancer (Table 1) 25,26,27 and its expression is controlled by nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of the cellular redox state, 28 highlighting the importance of xCT in an oxidative stress-resistant cancer cell phenotype
The performance comparison of PSPH expression against known immune response signatures revealed that PSPH expression in GBM patients functions as a potential biomarker to predict immunotherapy responses (PSPH, HR = 4.475, 95% CI = 1.33415.02, p = 0.0104)
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