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However, semaglutide is FDA-approved with established long-term safety data, while retatrutide is still investigational
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Semaglutide is also FDA approved for reducing cardiac risk in patients with Type 2 DM
Side effects can restart Because tirzepatide activates an additional receptor pathway, some GI side effects (nausea, bloating) can reappear briefly during re-titration even after a person was fully adjusted to semaglutide
Mice were single-housed in cages equipped with a running wheel (23 cm in diameter, Techniplast)
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