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Tirzepatide, also known as Zepbound for weight management, is an FDA-approved medication that targets two hormonal pathwaysGLP-1 and GIP receptorsto enhance weight-loss outcomes

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20% fewer heart attacks

In that case, clinicians will typically consider safer or better-suited alternatives and set up more intensive monitoring if semaglutide is used

Personalized GLP-1 may also be a more cost-effective option for some patients