Subsequently, to verify the effect of different GSH levels on NSBSO toxicity in the same cell lines, we pretreated 4T1 and CT26 cells with different concentrations of GSH before NSBSO treatment
The lower dose (100 mg vs 500 mg in standard reduced products) reflects the theoretically higher bioavailability of the acetylated form
(4) M Alba, D Fintini, A Sagazio, B Lawrence, et al (2006) Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse American Journal of Physiology, Endocrinology & Metabolism, 2006 Dec, Volume 291 (Issue 6), Pages E1290-4
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The cytosolic CHAC proteins have a GCT-fold, which places them within the GCT protein family (Kumar et al., 2012