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Clinical research established that the most commonly effective range is 250-500 mcg (0.25-0.5 mg) administered once daily via subcutaneous injection
Pregnant or nursing mothers, or individuals with a known medical condition, should not use or experiment with this product
There is an online resource to find licensed physicians called IMHH.org
The lack of a beneficial effect of selenium supplementation was supported in a 2014 meta-analysis of randomized controlled trials (67)
10.1007/s00204-012-0919-y Arch
The precise mechanism of action of Contrave is unknown though it is believed to work by targeting the hypothalamic melanocortin system (Figure 2) and the mesolimbic reward system 59
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