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539 Results from several Phase III clinical trials (ORION-9/10/11, NCT03397121, NCT03399370, and NCT03400800) have shown that subcutaneous injections of inclisiran every 6 months considerably reduce LDL-C levels by 4852%, demonstrating sustained efficacy and good tolerability

have reported: Gastroparesis (stomach paralysis) Severe abdominal pain Pancreatic cancer Gallbladder disease (including surgical removal) Intestinal obstruction or blockage Life-threatening dehydration or malnutrition Many of these conditions require hospitalization, invasive procedures, or long-term medical care

The result is a medication tailored to support your body during the weight loss journey, not just one that suppresses appetite

Neither company has given extremely granular guidance

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