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Some PK studies report an increased theoretical risk of toxicity with advancing age [62,63,64,65,66,67] due to prolongation of t 1/2 [62, 63], reduced paracetamol clearance [64, 67], increased paracetamol oxidation caused by a reduction in glucuronidation and sulphation capacity [65] or a reduction in liver volume [66]

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Though scientifically & statistically significant, in real world applications their advantage may not be clinically significant, especially when 90% of patients underdose their sunscreen

Studies, predominantly in animal models, have explored its effects on wound healing, tendon and ligament repair, gut health, and neuroprotection

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