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(2006) 142C:7785
doi: 10.1016/j.rmcr.2020.101063 27 IbrahimH
One should also consider that bacterial fermentation processes can convert the amino acids lysine, ornithine, and tyrosine into cadaverine, putrescine, and tyramine, which can be problematic in biogenic amine intolerance
CJC-1295 Without DAC and DPP-4 Resistance Research Research that led to the identification of the tetrasubstituted GRF backbone confirmed that all maleimido derivatives of hGRF(1-29) sharing the same four amino acid substitutions showed enhanced in vitro stability against DPP-IV and retained bioactivity in GH secretion assays in cultured rat anterior pituitary cells establishing that the tetrasubstituted scaffold itself is responsible for DPP-4 resistance, independent of the DAC albumin-binding moiety
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