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Benefits, Risks, and Medical Uses
Semaglutide and tirzepatide offer convenient weekly dosing
Eli Lillys GLP-1 offering, tirzepatide, launched shortly after (as Mounjaro for T2D in 2022 and Zepbound for obesity in 2023), demonstrated greater HbA1c reduction and up to a 20% placebo-adjusted weight loss
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It causes notable side effects including insomnia, night sweats, and cardiovascular strain
Poulter, S
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