GLP-1 receptor agonists work through several complementary mechanisms to improve glycaemic control
Tirzepatide is an FDA-approved prescription medication marketed as Mounjaro for type 2 diabetes mellitus and Zepbound for chronic weight management in adults with BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity
This marks a significant milestone in the diabetes treatment landscape as it introduces a more affordable option for patients managing type 2 diabetes
Methods A systematic review was conducted in PubMed, Web of Science and Google Scholar following PRISMA 2020 guidelines (PROSPERO: CRD42023445567)
Most protocols then move to 200 mcg per shot in week 2
The federal agency further warns of inflammation of the pancreas, gallbladder problems, low blood sugar, acute kidney injury, damage to the eyes retina, increased heart rate, and suicidal behaviour or thinking