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Gut Microbiome as a Novel Cardiovascular Therapeutic Target

However, in most cases the translation to the clinical setting is hampered by the lack of safety data in humans for the respective protective agents

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Concurrently, the imbalance characterized by reduced beneficial bacteria such as Bifidobacterium and Lactobacillus , and proliferation of opportunistic pathogenic bacteria such as Enterobacteriaceae and Streptococcus significantly disrupts gut immune homeostasis, promoting chronic low-grade inflammation (Liu Y

An earlier LEGEND Hypertension study, published in The Lancet, found that thiazide diuretics were more effective and caused fewer side effects than ACE inhibitors when used as first-line antihypertensive drugs

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