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Common injection sites include the abdomen (at least 2 inches from the navel), front of thighs, and back of upper arms

They may suggest lifestyle changes, medication adjustments, or other treatments before recommending stopping semaglutide

Oncogenesis 5 , e193 (2016)

Semaglutide acts as a GLP-1 receptor agonist, which means it mimics the GLP-1 hormone naturally produced in the intestines

Straino, S., Di Carlo, A., Mangoni, A., De Mori, R., Guerra, L., Maurelli, R., Panacchia, L., Di Giacomo, F., Palumbo, R., Di Campli, C., Uccioli, L., Biglioli, P., Bianchi, M

The STEP clinical trials reported larger average percentage weight loss compared with results observed in the SCALE studies