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Diabetes Care 39 , 17021710 (2016)

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The distribution and the concentration of vitamin C in the organs depend on the ascorbate requirements of each and on the tissue distribution of sodium-dependent vitamin C transporter 1 and 2 (SVCT1 and SVCT2)

This provides preliminary human evidence that the tested formulation reached biologically relevant compartments

In addition, because the acylcarnitine ester pool in the extracellular fluid is increased following the L-carnitine infusion, L-carnitine can enter the intracellular pool for utilization before clearance [15]