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In the central nervous system, semaglutide acts on GLP-1 receptors in areas of the brain that regulate appetite and food intake, particularly the hypothalamus

Unlike investigational compounds that simultaneously activate multiple receptor systems, Semaglutide provides researchers with a focused model for examining GLP-1 receptor biology and the molecular mechanisms associated with selective receptor activation

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GLP-related research Semaglutide, tirzepatide, retatrutide, and related research products