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The SELECT trial followed patients for over three years and demonstrated cardiovascular safety, even showing a 20% reduction in major adverse cardiovascular events
It's one of the few structures in the human body that, once damaged, is severely limited in its ability to repair itself [21]
The loss of compounded GLP-1s is challenging, but its an opportunity for providers to step in and advocate for their patients and refer appropriately when the Bariatric Center is the best option, says Dr
Multiple studies reviewed in this article document the diverse effects of these drugs on the glucagon-like peptide-1 receptors that are widely expressed in the human body, including the nervous system modulating appetite, the gastrointestinal tract modifying gastric emptying, and lipid metabolism regulation leading to reduction in fat deposition
Dietary modifications that may support metabolic health include: Including a source of protein at each meal, as protein can stimulate GLP-1 release Including dietary fibre , particularly soluble fibre from vegetables, legumes, oats, and wholegrains, which may promote GLP-1 secretion through fermentation by gut bacteria Eating regular, balanced meals that align with the NHS Eatwell Guide recommendations Limiting ultra-processed foods high in refined carbohydrates and unhealthy fats Considering fermented foods such as yoghurt, kefir, and sauerkraut, which may benefit overall gut health, though direct effects on GLP-1 require further research Lifestyle factors that support metabolic health include: Regular physical activity , with both aerobic exercise and resistance training showing benefits for glucose metabolism
Pharmaceuticals, 18(3), 399
