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Frontiers in Endocrinology, 16 , 1520362

The lipid in question is primarily comprised of polyunsaturated and monounsaturated fatty acids

DAMPs released during MI/R can activate the complement cascade, which up-regulates adhesion molecules on endothelial cells to promote neutrophil migration (139)

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Its main mechanism of action is based on increasing the expression of BDNF (Brain-Derived Neurotrophic Factor) and its TrkB receptors in the hippocampus and prefrontal cortex, promoting synaptic plasticity, long-term potentiation (LTP), and memory consolidation (Dolotov et al., Neuroscience 2006)

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