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This observation indicates that a single copy of HIF1a sufficiently supports adult neurogenesis and that HIF1a hemizygosity does not influence the efficacy to generate hippocampal adult-born neurons under normal circumstances

however, detailed batch traceability and testing methodology transparency are limited

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In SURMOUNT-1 , once-weekly tirzepatide in adults with obesity produced substantial, dose-dependent mean weight reductions over roughly 72 weeks versus placebo

Short-lived stinging or burning right after injection