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The hygroscopic nature of peptides means absorbed water causes the powder to aggregate
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Discontinuation has been linked with rapid weight gain in pregnancy, a higher chance of preterm delivery, and a greater risk of conditions like gestational diabetes and high blood pressure
One study found that within one year, 46.5% of those with diabetes and 64.8% of those without had ceased the drug
Therefore, systematic evaluation of vitamin B12 status should be considered an essential component of the diagnostic workup for diabetic peripheral neuropathy, particularly in patients with concurrent metformin or PPI therapy, to ensure accurate diagnosis and optimize therapeutic interventions
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