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Endocr Rev (2021) 42(2):10132
This GHR upregulation sensitises local cells to circulating GH, potentiating GH-induced JAK2/STAT signalling and stimulating collagen matrix synthesis, IGF-1 production, and fibroblast proliferation providing a mechanism through which BPC-157 engages the GH/IGF-1 axis at the tissue level without altering systemic GH secretion
Risk and protective factors of neurocognitive disorders in older adults in central and Eastern Europe: a systematic review of population-based studies
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8 This study, which took place over a five-year period, surely contributed to the FDAs approval of semaglutide in early 2024 for use in this population, and demonstrated that, in addition to managing diabetes and obesity, GLP1 receptor agonists offer value in reducing cardiovascular event risk
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