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Mechanism of Action (Based on Research) The combination of BPC-157 and TB-500 has drawn interest in preclinical studies due to their complementary mechanisms in supporting tissue repair, cellular regeneration, and inflammation control
Goal: Support metabolic homeostasis, insulin sensitivity, and age-related physical performance based on preclinical evidence [1] [2] [4]
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The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases
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