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People carrying loss-of-function variants in GLP1R may require higher tirzepatide doses to achieve the same appetite reduction as carriers of common alleles
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These medications should be discontinued before planned conception according to drug-specific guidelines: at least 2 months before for semaglutide, at least 1 month for tirzepatide, and when pregnancy is recognized for other agents
Glutathione reduces melanin production in the skin, resulting in an even and radiant complexion
This work was supported by Integrated Chinese and Western Medicine (YC-2023-0404), Fudan Zhangjiang Clinical Medicine Innovation Fund Project (KP0202118), Fudan Good Practice Program of Teaching and Learning (FD2023A227), Project of Key Medical Discipline of Pudong Hospital of Fudan University (Zdxk2020-11), Project of Key Medical Specialty and Treatment Center of Pudong Hospital of Fudan University (Zdzk2020-24), Pudong New Area Clinical Plateau Discipline Project (PWYgy-2021-03), the Natural Science Foundation of China (21675034), National Natural Science Foundation of China (81370932), Shanghai Natural Science Foundation (19ZR1447500), Pudong New Area Clinical Characteristic Discipline Project (PWYts2021-11), Pudong New Area Clinical Characteristic Discipline Project (PWYts2021-01), Pudong Research Project (YC-2023-0202, YC-2023-0607, PWRI2023-08), Wenzhou Medical University Education Grant (JG2021197), Pudong Research Project (PWRl2023-08, YC-2023-0128
