You'll take one pill each morning on an empty stomach, followed by a 30-minute fast
This retrospective cohort study drew on TriNetX, a US healthcare database encompassing more than 150 million patients
There's at least some improvement trend, even if small
The mechanism likely involves rapid changes in retinal blood flow, increased vascular permeability, and alterations in growth factor expression as glucose levels normalize
In contrast with SGLT2 inhibitors, GLP-1 RAs have only a modest effect on the risk of HF hospitalization
Obesity disrupts bone metabolism and leads to increased bone resorption, but GLP-1RAs can inhibit this damage and improve bone health by increasing the OPG/RANKL ratio, reducing osteoclast activity, and promoting bone formation