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Recovery after training or daily wear and tear Better sleep-time repair , when the body does most of its rebuilding Lean body-composition goals Overall vitality and performance Studied in the context of overnight GH-pulse rhythms and post-training recovery

GLP-1 initiators had higher rates of metformin use (32.7% vs

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In a recent meta-analysis of 12 observational studies of patients with T2DM treated with either SGLT2 inhibitors or GLP-1RAs, the GLP-1RA group exhibited a significantly lower relative risk of lower limb amputation vs the SGLT2 inhibitor cohort (3.54 vs 4.72 events per 1000 patient-years).37 Furthermore, in the CANVAS program involving 10,142 patients with T2DM at high cardiovascular risk, canagliflozin was found to be associated with a 1.97-fold increased risk of lower-limb amputations

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