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[20] [21] According to the UK product information, if you use oral contraceptives, you should use additional or alternative non-oral contraception for 4 weeks after starting Mounjaro and for 4 weeks after each dose increase

Having these conversations upfront prevents the common scenario where a patient starts tirzepatide, experiences symptoms of thyroid overmedication, and does not get labs drawn for months because nobody specified when to test

During this phase, patients may observe steady weekly or monthly reductions in body weight

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The landmark STEP 1 trial for semaglutide, published in The New England Journal of Medicine , provided crucial insight into this issue