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Sebuah studi pada tahun 2017 menjelaskan bahwa glutathione dapat membantu meningkatkan elastisitas dan kekencangan kulit, sehingga mengurangi kerutan dan garis halus, sekaligus membantu menghambat tanda-tanda penuaan dini akibat kerusakan radikal bebas

Biotransformation of endocrine disrupting compounds by selected phase I and phase II enzymes--formation of estrogenic and chemically reactive metabolites by cytochromes P450 and sulfotransferases

In one study with participants consuming 6mg of astaxanthin per day and applying a topical solution containing astaxanthin showed positive results in 8-weeks (30 Healthy Female Adults)[vi] One study that did a comprehensive review of the use of astaxanthin on skin health, repair, and disease concluded that astaxanthin is a promising compound in the field of dermatology

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:Basic cofactors consist of: Vitamins A and Vitamin D (11,000 IU and 3000 5000 IU respectively) Vitamin C at 4000+ mg per day Vitamin E B vitamin complex with P5P, biotin and pantethine (without including cyano B12 or folic acid) A 1:1 magnesium:calcium supplement Zinc, 50 mg per day Omega 3 fatty acids, 2-6 caps per day Optional Basic Cofactors include: Glycophospholipids Additional pantethine Multimineral supplements (choline, selenium) Alpha lipoic acid D-Ribose CoQ-10 Titrate B12s while adjusting methylfolate and potassium Methylcobalamin (MeB12) should start at 15-20 mg per day Adenosylcobalamin (AdoB12) should start at 10 mg per week Titrate methylfolate to sufficiency, starting at 1 mg Titrate L-carnitine fumarate (LCF) to effectiveness, starting at 125 mg per day and aiming for 500-1000 mg per day, stopping when an increase of 250 mg makes no difference

The duration of the result is also influenced by lifestyle and sun exposure habits