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LOH explained a significant proportion of lost SNVs and indels in late disease (Fig
The GLP-1 biosimilars market is primarily driven by the rapidly increasing global prevalence of type 2 diabetes and obesity, rising demand for affordable biologic therapies, and the impending patent expirations of major originator GLP-1 drugs such as semaglutide and dulaglutide
Common risk factors include structural predispositions, such as a crowded optic disc and optic disc drusen (ODD), and systemic conditions like sleep apnea syndrome, hypertension, hyperlipidemia, nocturnal hypotension, diabetes mellitus, and hypercoagulability [1, 2]
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