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Yao H et al
In general, most hydrophobic BAs are considered as FXR agonists, while hydrophilic non-12-OH TMCA, UDCA, and T(G)UDCA serve as endogenous FXR antagonists 4,9,10
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
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These medications have shown positive outcomes in dyslipidemia with much of the impact being on triglycerides
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