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Gu G, Roland B, Tomaselli K, Dolman CS, Lowe C, Heilig JS (2013) Glucagon-like peptide-1 in the rat brain: distribution of expression and functional implication

Common complaints include: Increased tooth decay or cavities Some individuals notice new dental caries or worsening of existing decay, particularly along the gum line or between teeth Gum problems Gingivitis (gum inflammation), bleeding gums, receding gums, or periodontal disease may develop or worsen Tooth sensitivity Heightened sensitivity to hot, cold, or sweet foods and beverages Dry mouth (xerostomia) A persistent feeling of oral dryness, which can compromise the mouth's natural protective mechanisms Bad breath (halitosis) Persistent unpleasant breath odour that does not improve with routine oral hygiene Tooth discolouration or erosion Changes in tooth appearance, including yellowing, thinning of enamel, or visible wear patterns These symptoms may be indirectly related to the medication's mechanism of action and common adverse effects

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Pharmacokinetic modeling suggests that heavier patients may have slightly lower peak concentrations, but the FDA-approved dosing regimen does not require weight-based adjustments

This is the most common and most benign cause of elevated B12